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Annexin V在核医学细胞凋亡显像中的应用

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Author:: No author available

Journal Title:: CHINESE JOURNAL OF NUCLEAR MEDICINE

Issue:: 6

DOI:: 10.3760/cma.j.issn.2095-2848.2004.06.032

Key Word:: No keyword available

Abstract： @@ 细胞凋亡是细胞内在的决定生物体发育和组织平衡的一个重要机理,如果这个受到严密调控的细胞自杀机理发生功能障碍或失去控制,将导致肿瘤、神经退行性疾病或许多其他的病理性改变[1-3].细胞凋亡的测定,已成为评估肿瘤疗效的一项新指标,进一步提高肿瘤细胞凋亡与增殖的比值是临床化疗的新要求;此外,细胞凋亡实验也是筛选抗癌新药的快速、有效方法.细胞凋亡显像研究正在成为核医学新的发展热点[4-6].笔者对磷脂结合蛋白V(Annexin V)在细胞凋亡显像中的应用综述如下.

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