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基于功能MR成像在遗传学研究中的进展
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- Author:
- No author available
- Journal Title:
- Chinese Journal of Radiology
- Issue:
- 1
- DOI:
- 10.3760/cma.j.issn.1005-1201.2014.01.021
- Key Word:
- No keyword available
Abstract： 新的基因组学技术的发展影响着医学的每一个领域[1].在2000年以前的研究中,医学影像学几乎没有考虑到受试者的遗传学背景,而遗传学研究也仅仅局限在行为层面.随着遗传学及医学影像学的快速发展,特别是功能MRI技术的兴起,通过统计学方法,将这两个领域有机地结合了起来,产生了一门新的学科,即影像遗传学(imaging genetics)[2].近10余年来,影像遗传学有了快速发展[3].笔者从遗传学基本概念、功能MRI的主要方法、临床应用、存在问题等方面进行叙述.一、遗传学基本概念影像遗传学是指用影像学的方法来研究遗传对不同个体所产生影响的一门新兴交叉学科.其涉及到影像学和遗传学两门学科的知识,长时间以来,这两个学科间几乎没有交集,影像科医师对遗传学领域一些新的概念比较陌生,为了便于更好的理解,下面介绍影像遗传学中经常用到的几个遗传学概念.
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