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A comparative study of MR imaging scores and MR perfusion imaging in pre-operative grading of intracranial gliomas
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF RADIOLOGY
- Issue:
- 2
- DOI:
- 10.3760/j.issn:1005-1201.2005.02.009
- Key Word:
- 神经胶质瘤;病理学,临床;磁共振成像;对比研究
Abstract： 目的比较MR积分法与灌注成像在脑胶质瘤术前分级诊断中的价值.方法对30例脑胶质瘤(低级8例,高级22例,世界卫生组织分级)术前行MR常规及灌注成像检查.MR积分法使用9个指标进行评价,灌注指标相对脑血容量(rCBV)由肿瘤及对侧正常脑白质的脑血容量(CBV)相比后得出.分别对低级、Ⅲ级和Ⅳ级胶质瘤的积分及rCBV值进行分析.结果低级胶质瘤的积分值(0.67±0.29)显著低于Ⅲ级(1.32±0.47)( t=-3.48,P=0.003)和Ⅳ级(1.56±0.20) (t=-7.36,P=0.000).Ⅲ级和Ⅳ级之间差异无统计学意义(t=-1.39,P=0.182).低级胶质瘤的rCBV值(2.38±0.66)显著低于Ⅲ级(5.81±3.20) (t=-3.57,P=0.003)和Ⅳ级(6.99±2.47) (t=-5.09,P=0.001).Ⅲ级和Ⅳ级之间差异无统计学意义(t=-0.93,P=0.365).结论在脑胶质瘤术前分级诊断中,常规MR和灌注成像均有重要价值,可相互补充,提高诊断准确率.
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