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妊娠合并遗传性凝血因子Ⅶ缺乏症二例报告并文献复习
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- Author:
- No author available
- Journal Title:
- Chinese Journal of Obstetrics and Gynecology
- Issue:
- 11
- DOI:
- 10.3760/cma.j.issn.0529-567x.2014.11.012
- Key Word:
- No keyword available
Abstract： 遗传性凝血因子Ⅶ(factorⅦ,FⅦ)缺乏症是由于FⅦ基因异常而引起FⅦ活性水平下降所导致的一种遗传性凝血功能障碍性疾病.目前的研究认为,本病为常染色体隐性遗传性疾病,发病率为1/500 000～1/300 000[1],临床表现可为鼻出血、皮肤黏膜出血、月经过多以及脑出血等症状,也可完全无症状.妊娠合并遗传性FⅦ缺乏症罕见,至今为止国外仅有数十例报道,国内尚无类似病例报道.为进一步提高临床医师对妊娠合并遗传性FⅦ缺乏症的认识,本文对北京大学人民医院产科近期收治的2例妊娠合并遗传性FⅦ缺乏症患者的临床资料进行分析,并结合文献复习对妊娠期相关问题进行探讨.
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