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卵巢癌患者BRCA1基因突变及临床意义
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF OBSTETRICS AND GYNECOLOGY
- Issue:
- 4
- DOI:
- 10.3760/j.issn:0529-567X.2003.04.023
- Key Word:
- No keyword available
Abstract： @@ 乳腺癌-卵巢癌易感基因(BRCA1)的克隆[1] ,为卵巢癌发病机制的研究提供了新方向.为了探讨其与人卵巢癌发生的关系,本研究检测了卵巢癌患者BRCA1基因胚系突变.
- [1]Y, Miki,J, Swensen,D, Shattuck-Eidens,etc.A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.[J].1994,266.
- [2]S C, Rubin,M A, Blackwood,C, Bandera,etc.BRCA1, BRCA2, and hereditary nonpolyposis colorectal cancer gene mutations in an unselected ovarian cancer population: relationship to family history and implications for genetic testing.[J].1998,178(4).