You Position: Home > Paper
孕妇外周血中胎儿细胞及DNA分离方法的比较
( views:218, downloads:12 )
- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF OBSTETRICS AND GYNECOLOGY
- Issue:
- 11
- DOI:
- 10.3760/j.issn:0529-567X.2001.11.020
- Key Word:
- No keyword available
Abstract： @@ 产前非创伤性诊断技术是国内外围生学关注的重要课题.近10年来,由于相关分子生物学、流式细胞学技术的进展,人类对研究母亲外周血中胎儿细胞的工作迈进了一大步.但由于母血中胎儿细胞甚微,分离及纯化胎儿细胞的技术难点尚未解决,使该技术还无法在临床上广泛应用.本研究旨在探索可靠稳定的分离胎儿细胞和DNA的方法,为产前诊断奠定基础.
- [1]Jan C. Oosterwijk,Cecile F.H.M. Knepflé,Wilma E. Mesker,etc.Strategies for Rare-Event Detection: An Approach for Automated Fetal Cell Detection in Maternal Blood[J].1998,63(6).
- [2]D W, Bianchi,K W, Klinger,T J, Vadnais,etc.Development of a model system to compare cell separation methods for the isolation of fetal cells from maternal blood.[J].1996,16(4).
- [3]Jestice K,Hackett G,Griffin DK,etc.Evaluating the culture of fetal erythroblasts from maternal blood for non-invasive prenatal diagnosis.[J].1998,18(9).
- [4]Tolley E,Utermohlen J,Sammons D,etc.Charge flow separation: quantification of nucleated red blood cells in maternal blood during pregnancy.[J].1998,18(5).
- [5]马旭,张思仲,赵丽.孕妇外周血中转铁蛋白受体阳性细胞来源的初步分析[J].1996,(6).