Abstract: Objective To compare the therapeutic effects of different remedis in patients with endometrial carcinoma. Methods Total of 386 patients with metracarcinoma underwent 3 different treatments: (1) operation only 145 cases; (2) operation and complemental radiotherapy 161 cases; (3) radiotherapy only 80 cases. Then they were followed up for 5 years and more. Results The 5-year survival rates of operation group were 78.9% (56/71), 61.0% (25/41) and 18.2% (6/33) in stage Ⅰ, stage Ⅱ, and stage Ⅲ~Ⅳ respectively, for operation and complemental radiotherapy,they were 75.0% (33/44), 59.5% (44/74) and 48.8% (21/43), for radiotherapy, 34.8% (8/23), 18.8% (3/16) and 0.0% (0/41). There was no difference between operation group and operation plus radiotherapy in patients with stage Ⅰ and stage Ⅱ (P>0.05). However the 5-year survival rates were significantly higher in operation plus complemental radiotherappy group and those only received operation in stage Ⅲ stage Ⅳ patients (P<0.001). And no matter in what stages, the therapeutic effect was worse in radiotherapy group than other two groups (P<0.001). Conclusion The remedis with operation as main measure are the best choice for metracarcinoma, radiotherapy merely is fit with those who can not be operated on.