Abstract： To the Editor:A 73-year-old man presented with erythemas on his trunk and limbs with significant itching,which he had experienced for 11 months [Figure 1A and 1B].Histological examination of his skin biopsy revealed sub-epidermal blister formation with eosinophilic and lymphocytic infiltration in the dermis.Direct immunofluorescence revealed the presence of a linear deposition along the basement membrane zone (BMZ).Indirect immunofluorescence revealed that the patient's serum was positive (titer ＞1:320) for anti-BMZ antibodies.Anti-BP180 antibody was 102U/mL.Based on these findings,a diagnosis of bullous pemphigoid (BP) was established.