Abstract： Type 2 diabetes (T2D) is the most common cause of chronic kidney disease (CKD) and end-stage renal disease worldwide.In China,approximately 21.3％ of diabetes was estimated to accompany with CKD and the number of diabetes-related CKDs was 24.3 million,of whom 60.5％ preserved renal dysfunction with slightly increased albuminuria.[1,2] In the light of the prevalence and massive health and financial toll,the pathologic diagnosis and prognosis of diabetes-related CKD are of great clinical and societal relevance.Therefore,based on the different pathological types of diabetes with renal impairment,appropriate therapeutic schedules largely impacted on the prognosis of diseases.It was well worthy to summarize the relationship between pathology and prognosis for T2D with renal involvement in the study.