Research Progress on Chemical Constituents,Pharmacological Effects and Clinical Application of Lightyellow Sophora Root
- Author:
- No author available
- Journal Title:
- Chinese Journal of Drug Abuse Prevention and Treatment
- Issue:
- 1
- DOI:
- 10.15900/j.cnki.zylf1995.2024.01.020
- Key Word:
- 苦参;化学成分;药理活性;抗炎作用;lightyellow sophora root;Chemical composition;Pharmacological activity;Anti-inflammatory effect
Abstract： Lightyellow sophora root can not only clear dampness-heat,diuretic kill insects,but also dispel wind evil and relieve itching,which is widely used in clinic.The chemical composition of lightyellow sophora rootis complex and diverse,which is the intrinsic basis of its pharmacological activity.In addition,modern pharmacological studies have found that lightyellow sophora root has certain pharmacological effects in anti-inflammatory and antibacterial,anti-arrhythmia,hypnotic and sedative,anti-tumor,hypoglycemic and other fields,but the exact mechanism of action is not well understood.In this paper,the chemical composition,pharmacological action and clinical application of lightyellow sophora root are summarized in order to provide sufficient theoretical basis for the clinical application and scientific research of Chinese medicine lightyellow sophora root in the future.
- [1]黄琦,屈玟珊,高世军,等.苦参生物碱和黄酮体外抑菌活性比较[J].2016,(5).
- [2]武金银.苦参素治疗慢性乙型肝炎的临床疗效观察[J].2010,(15).
- [3]何旭东,符忠宇,黄颖,等.苦参异戊烯基黄酮的化学成分及生物活性研究进展[J].2022,27(8).
- [4]张钟媛.苦参的化学成分和药理作用研究进展[J].2015,(6).
- [5]陈慧芝,包海鹰,诺敏,等.苦参的化学成分和药理作用及临床研究概况[J].2010,(3).
- [6]吴燕燕.苦参镇静安神有效成分的分离及药效研究[D].2016.
- [7]张建荣,刘志刚,李玉芳,等.苦参素对肝脏纤维化的抑制作用[J].2012,(22).
- [8]杨颖杰,傅钰,顾美芳,等.苦参中黄酮类化合物的药理作用[J].2013,(3).
- [9]唐经凡.苦参的药用价值[J].2008,(2).
- [10]王继光,吕高虹.苦参总黄酮抗实验性心律失常作用的研究[J].2001,(5).
- [11]刘芬,刘洁,陈霞,等.氧化苦参碱的抗炎作用及其机制[J].2005,(5).
- [12]蒋树中,张毅刚,付强.苦参抗心律失常作用电生理机制研究[J].2004,(21).
- [13]胡珍真,高妍,张杰.苦参凝胶临床应用研究进展[J].2014,(21).
- [14]杜亚萍,宋光耀,王富军,等.氧化苦参碱对胰岛素抵抗的影响及其作用机制[J].2015,(16).
- [15]张翅,马悦,高慧敏,等.苦参化学成分研究进展[J].2014,(4).
- [16]李娟,姚遥,韩怀钦,等.苦参碱对LPS诱导的阿尔茨海默病小鼠模型学习记忆功能和脑内神经炎症的影响[J].2018,(24).
- [17]张明发,沈雅琴.氧化苦参碱对皮肤疾病的药理作用与临床应用研究进展[J].2020,(4).
- [18]王秀坤,李家实,魏露雪.苦参中脂肪酸成分的研究[J].1994,(3).
- [19]王金侠,张立,矫增金,等.苦参碱及氧化苦参碱诱导肿瘤细胞自噬作用机制研究进展[J].2021,(2).
- [20]张明发,沈雅琴.苦参碱防治高血糖、高血脂症及其并发症的药理机制研究进展[J].2022,45(2).
- [21]宋雪,王成祥,袁姣姣,等.苦参对特应性皮炎模型小鼠皮损组织PAR-2、TrK-A蛋白表达的影响[J].2022,63(9).
- [22]王秀坤,李家实,魏璐雪.苦参挥发油成分的研究[J].1994,(9).
- [23]鲍淑娟,李淑芳,周文正,等.苦参碱平喘作用机理探讨[J].1995,(5).
- [24]李凡,杨远贵,谷丽华,等.苦参的化学成分及生物活性研究进展[J].2021,(10).