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Research Progress on the Clinical Application and Mechanism of Action of Ephedra

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Author:
No author available
Journal Title:
Chinese Journal of Drug Abuse Prevention and Treatment
Issue:
1
DOI:
10.15900/j.cnki.zylf1995.2024.01.019
Key Word:
麻黄;肺系疾病;心脑血管疾病;肾病;麻黄碱;伪麻黄碱;药理毒性;Ephedra;Pulmonary diseases;Cardiovascular and cerebrovascular diseases;Kidney disease;Ephedrine;Pseudoephedrine;Pharmacotoxicity

Abstract: Ephedra is one of the commonly used drugs in traditional Chinese medicine clinical practice,which has the effects of sweating,relieving external symptoms,promoting lung function,relieving asthma,promoting diuresis,and reducing swelling.It has significant effects in the treatment of lung diseases,cardiovascular and cerebrovascular diseases,kidney diseases,and other diseases.The main active ingredients of ephedra are ephedrine,pseudoephedrine,flavonoids,ephedra polysaccharides,etc.They have various functions such as antibacterial,antiviral,immune regulation,antioxidant activity,etc.However,ephedra has certain pharmacological toxicity.Clinical practice should pay attention to strict control of related products,prohibit excessive dosage and long-term use,and ensure medication safety.This article mainly reviews the clinical application and mechanism of action of ephedra,aiming to provide reference basis for clinical application and ephedra research.

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