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The role of competitive endogenous RNAs in the pathogenesis of diabetic retinopathy

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Author:: No author available

Journal Title:: Chinese Journal of Diabetes

Issue:: 11

DOI:: 10.3969/j.issn.1006⁃6187.2022.11.013

Key Word:: 糖尿病视网膜病变;竞争性内源RNA;微小RNA;信使RNA;基因调控

Abstract： DR是糖尿病微血管病变过程中眼底特异性改变重要表现,也是引起失明的主要原因.竞争性内源RNA(ceRNA)是一种全新基因表达调控模式,较其他调控网络更精细和复杂,涉及RNA分子更丰富.ceRNA分子机制可影响彼此表达水平,在多种疾病病理生理中起重要作用.DR发生发展不仅存在ceRNA调控网络的相互作用,且ceRNA调控发挥重要作用.本文对ceRNA在DR发生机制中的调控作用进行综述.

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