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Research progress in relationship between Zinc-alpha 2-glycoprotein and type 2 diabetes mellitus

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Author:: No author available

Journal Title:: Chinese Journal of Diabetes

Issue:: 8

DOI:: 10.3969/j.issn.1006-6187.2016.08.022

Key Word:: 锌α2糖蛋白;糖尿病,2型;Zinc-alpha 2-glycoprotein(ZAG);Diabetes mellitus,type 2

Abstract：锌α2糖蛋白(ZAG)是一种新型脂肪细胞因子,存在于人体血浆及多种体液中.最初认为,ZAG参与肥胖、脂代谢调节,近年发现,ZAG与T2DM关系密切.ZAG可通过增加IS、提高组织葡萄糖代谢率、结合β3肾上腺素受体等机制发挥抗糖尿病作用.探讨ZAG与T2DM的相关性,有助于为T2DM的早期干预和治疗提供新思路.

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