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A study on the changes in levels of serum 25-hydroxyvitamin D3 and fibroblast growth factor-23 in the T2DM patients with hypertension
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- Author:
- No author available
- Journal Title:
- Chinese Journal of Diabetes
- Issue:
- 7
- DOI:
- 10.3969/j.issn.1006-6187.2013.07.013
- Key Word:
- 糖尿病,2型;高血压;血清25羟维生素D3;成纤维细胞生长因子23;Diabetes mellitus,type 2;Hypertension;Serum 25-hydroxyvitamin D3 [25-(OH)D3];Fibroblast growth factor-23 (FGF23)
Abstract： 目的 了解血清25羟维生素D3[25-(OH)D3]与成纤维细胞生长因子23(FGF23)水平在T2DM合并高血压患者中的变化趋势. 方法 选取T2DM合并高血压患者40例(DH组),单纯T2DM患者40例(T2DM组),以及同期体检的健康者40名(NC组),检测血清25-(OH)D3和GF23水平及各项临床生化指标. 结果 T2DM组血清25-(OH) D3水平[(31.96±2.13)μg/L]低于NC组[(33.53±2.53)μg/L](P＜0.05),DH组25-(OH)D3水平[(30.82±2.83)μg/L]较T2DM组更低(P＜0.01).T2DM组FGF23水平[(1.80±0.09) μg/L]高于NC组[(1.14±0.09) μg/L] (P＜0.01),DH组FGF23水平-(1.86±0.08)μg/L]较T2DM组更高(P＜0.01). 结论 血清25-(OH)D3和FGF23水平与T2DM合并高血压有相关性.
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