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The correlation of albuminuria and glomerular filtration rate with diabetic retinopathy in type 2 diabetes
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- Author:
- No author available
- Journal Title:
- Chinese Journal of Diabetes
- Issue:
- 2
- DOI:
- 10.3969/j.issn.1006-6187.2012.02.008
- Key Word:
- 糖尿病视网膜病变;肾小球滤过率;尿白蛋白
Abstract： 目的 比较T2DM视网膜病变(DR)不同时期,尿蛋白、肾小球滤过率(GFR)变化,寻找早期筛查DR的指标. 方法 采用回顾性病历研究,根据散瞳眼底检查分组,同期测定各组24h尿白蛋白定量,以MDRD公式计算GFR. 结果 与正常眼底组相比,DR组患者的GFR明显减低(P＜0.05),且尿白蛋白(UAlb)、GFR均与DR呈显著独立相关(P＜0.05). 结论 UAlb、GFR均与DR密切相关,其联合筛查有利于DR早期检出.
- [1]叶威巍,鹿斌,龚伟,等.2型糖尿病和慢性肾脏病的相关性分析[J].2009,(4).
- [2]史浩,陈楠,张文,等.简化MDRD公式预测慢性肾病患者肾小球滤过率的应用评价及校正[J].2006,(9).
- [3]Kramer HJ,Nguyen QD,Curhan G,etc.Renal insufficiency in the absence of albuminuria and retinopathy among adults with type 2 diabetes mellitus.[J].2003,289(24).
- [4]T, Deckert,B, Feldt-Rasmussen,K, Borch-Johnsen,etc.Albuminuria reflects widespread vascular damage. The Steno hypothesis.[J].1989,32.
- [5]Alba, Morales.A better future for children with type 1 diabetes: Review of the conclusions from the Diabetes Control and Complications Trial and the Epidemiology of Diabetes Interventions and Complications study.[J].2009,106(4).
- [6]Jerums G,Premaratne E,MacIsaac RJ,etc.Integrating albuminuria and GFR in the assessment of diabetic nephropathy.[J].2009,5(7).
- [7]C.E. MOGENSEN,M.E. COOPER,H.-H. PARVING,etc.Poor prognosis in proteinuric type 2 diabetic patients with retinopathy: insights from the RENAAL study[J].2005,98(2).