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胰腺神经内分泌肿瘤肝转移的外科诊治现状和争议

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Author:: No author available

Journal Title:: Chinese Journal of Pancreatology

Issue:: 4

DOI:: 10.3760/cma.j.issn.1674-1935.2018.04.002

Key Word:: No keyword available

Abstract：神经内分泌肿瘤(neuroendocrine neoplasm,NEN)是起源于肽能神经元及神经内分泌细胞的异质性肿瘤,30％～80％的NEN患者存在同期或非同期肝转移,其5年生存率明显低于无肝转移患者.美国国立癌症研究所“监测、流行病学与最终结果数据库”显示,近30年来胰腺NEN(pNEN)的发病率呈逐步上升趋势,约占所有胃肠胰NEN的16％[1-2],其中肝转移是pNEN预后不良的关键因素[3].随着对疾病认识的不断深入,pNEN肝转移的诊断方法不断完善,治疗手段日益多样化,但其外科治疗方案的选择尚存争议.为此,笔者在pNEN组织病理分级及肝转移灶分型基础上阐述pNEN肝转移的外科诊治现状和争议.

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