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p27Kip 1和Ki-67抗原在胰腺导管腺癌中的表达及意义
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- Author:
- No author available
- Journal Title:
- CHINESE JOURNAL OF PANCREATOLOGY
- Issue:
- 4
- DOI:
- 10.3760/cma.j.issn.1674-1935.2007.04.017
- Key Word:
- No keyword available
Abstract： @@ 肿瘤的发生发展是多因素、多阶段、多因子作用的结果,其中癌基因的激活与抑癌基因的失活是其重要特征.抑癌基因p27Kip 1是CIP/KIP成员,是细胞周期的负调控因子.Ki-67核抗原的合成、表达与增殖细胞的增殖周期有关.本实验应用免疫组化SABC法检测p27Kip 1和Ki-67抗原在胰腺导管腺癌、CP和正常胰腺组织的表达,探讨它们在胰腺导管腺癌发病机制中的作用.
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