Abstract: Objective:To evaluate the efficacy of biofeedback for postoperative fecal incontinence in children with Hirschsprung disease(HD).Methods:A total of 50 children with congenital HD postoperative fecal incontinence underwent modified Soave's operation.The average age was 8.1(3.7-14)years.Anorectal manometry and Kelly's clinical score were employed for evaluating the severity of fecal incontinence.Biofeedback therapy instrument was applied with a therapeutic course of(7-10)days and the next course resumed after a week's rest.Meanwhile, the subjects instructed to take the initiative for pelvic floor muscle contraction training.And treatment protocols were personalized.Results:The follow-up period was(6-48)months.After treatment, resting anal pressure and maximal systolic pressure of anal canal spiked markedly.The longest contraction time of anal canal became prolonged and resting rectal pressure showed no obvious change before and after treatment.Maximal anal systolic pressure pre-treatment was(84.03±45.07)mmHg in mild group and(63.39±38.22)mmHg in severe group.After 6 therapeutic courses, maximal anal systolic pressure was(116.72±31.88)mmHg in mild group and(95.02±31.18)mmHg in severe group.Forty-three cases(86%)showed a complete disappearance of symptoms.After 3 therapeutic courses, there were a complete disappearance of symptoms(n=16, 32%)and improvements(n=27, 54%). And 7 cases(14%)showed some improvement of fecal incontinence with varying degrees of fecal contamination.Conclusions:Biofeedback is an effective and safe treatment for postoperative fecal incontinence in HD.Individualized treatments should be formulated in accordance with the severity of fecal incontinence in children.