Abstract： Objective To assess the feasibility and safety of total laparoscopic enterectomy and enteroanastomosis for digestive tract malformations in children.Methods From January 2015 to December 2015,8 children with digestive tract malformations undergoing laparoscopy were retrospectively analyzed.There were 6 boys and 2 girls with an average age of 64.8 (22-132) months.Operative caveats:They were placed in a supine position with tracheal intubation anesthesia.A 3.5 mm Trocar was inserted into left upper of umbilical wheel and another 5.0 mm Trocar into right lower.A third 5-ram Trocar was placed in lateral border of left/right rectus abdominis at the projection level of abdominal lesion sudace under direct vision.And 3.0 mm laparoscope was introduced into 3.5 mm troear for laparoscopy and two other Trocars for manual instruments.Under laparoscope,the lesion was identified.Enterectomy was then performed intracorporeally with ultrasonic knife.Intestinal wall was sutured with 4-0 wire and suspension was applied.Posterior intestinal wall was continuous fullthickness sutured by 5-0 absorbable thread (beyond lateral mesangial intestinal wall) and anterior intestinal wall was continuously sutured through seromuscular layer.Results Laparoscopy was performed for all patients.The mean operative duration was 1.9 (1.5-2.5) hours.Postoperative course was uneventful.Pathological examinations confirmed the diagnoses of Meckel' s diverticulum (n =3) and enteric duplication cysts (n =5).Conclusions Total laparoscopic enterectomy and enteroanastomosis is safe,feasible and effective for children with digestive tract malformations.However,therapeutic indications and contraindications should be strictly defined.