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2型糖尿病与轻度认知功能损害的相关性
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- Author:
- No author available
- Journal Title:
- PREVENTION AND TREATMENT OF CARDIO-CEREBRAL-VASCULAR DISEASE
- Issue:
- 1
- DOI:
- 10.3969/j.issn.1009-816X.2013.01.11
- Key Word:
- 2型糖尿病;轻度认知功能障碍;蒙特利尔认知评估量表
Abstract： 目的 对2型糖尿病患者进行认知功能评价,确定轻度认知功能障碍(MCI)的发生率及特点,为进一步防治MCI提供理论依据.方法 采用简易智能状态检查量表(MMSE)和蒙特利尔认知评估量表(MoCA)对90例2型糖尿病患者(观察组)、及128例健康体检老年人(对照组)进行认知功能评定,对结果进行统计学分析.结果 ①观察组患者MCI的发病率为36.7%(33/90)明显高于对照组的6.25%(12/192),两组差异有统计学意义(P<0.05);②观察组的MoCA评分及MMSE评分较对照组显著降低(P<0.05);观察组中的MCI患者在MoCA总分较对照组中MCI患者的水平低(P<0.05),而在MMSE评分两者差异无统计学意义(P>0.05).MoCA分项比较两组间的视空间与执行功能、注意、抽象、延迟回忆,差异有统计学意义(P<0.05),尤其延迟回忆损害最为明显(P<0.01).结论 2型糖尿病患者中MCI发生率较高,且MCI以延迟回忆损害最为明显.MoCA量表在评价MCI较MMSE量表敏感.
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