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配子及早期胚胎发育过程中的DNA甲基化动态改变
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- Author:
- No author available
- Journal Title:
- Journal of Practical Obstetrics and Gynecology
- Issue:
- 1
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Abstract： 近年来,随着对染色质 DNA、组蛋白、 RNA 化学修饰了解的深入,表观遗传学在胚胎发育、疾病发生发展中的生物学作用被逐步揭示. 其中,DNA甲基化作为一种重要的表观遗传学修饰,在基因表达调控与染色质结构调节中具有重要作用.
- [1]Shirane Kenjiro,Miura Fumihito,Ito Takashi,etc.NSD1-deposited H3K36me2 directs de novo methylation in the mouse male germline and counteracts Polycomb-associated silencing[J].2020,52(10).
- [2]Yamaguchi, Shinpei,Shen, Li,Liu, Yuting.Role of Tet1 in erasure of genomic imprinting.[J].2013,504(7480).
- [3]Sakuma, Tetsushi,Yokobayashi, Shihori,Saitou, Mitinori,etc.Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells[J].2015,17(2).
- [4]Dhayalan A,Rajavelu A,Rathert P,etc.The Dnmt3a PWWP domain reads histone 3 lysine 36 trimethylation and guides DNA methylation.[J].2010,285(34).
- [5]Chen, Xi,Lin, Hui,Yang, Daping,etc.Early-life undernutrition reprograms CD4(+) T-cell glycolysis and epigenetics to facilitate asthma[J].2019,143(6).
- [6]Yamaguchi, Shinpei,Hong, Kwonho,Liu, Rui,etc.Tet1 controls meiosis by regulating meiotic gene expression.[J].2012,492(7429).
- [7]Guo, Xue,Wang, Ling,Li, Jie,etc.Structural insight into autoinhibition and histone H3-induced activation of DNMT3A[J].2015,517(Jan.29 TN.7536).
- [8]Shinya Aramaki,Katsuhiko Hayashi,Kazuki Kurimoto,etc.A Mesodermal Factor, T, Specifies Mouse Germ Cell Fate by Directly Activating Germline Determinants[J].2013,27(5).
- [9]Li X,Ito M,Zhou F,etc.A maternal-zygotic effect gene, Zfp57, maintains both maternal and paternal imprints.[J].2008,15(4).