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LOCALIZATION AND EXPRESSION OF TR3 ORPHAN RECEPTOR IN MOUSE TESTIS
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- Author:
- No author available
- Journal Title:
- ACTA PHYSIOLOGICA SINICA
- Issue:
- 4
- DOI:
- 10.3321/j.issn:0371-0874.1998.04.012
- Key Word:
- 孤儿受体TR3;原位杂交;免疫组织化学;精子发生
Abstract： 本文采用原位杂交和免疫组织化学技术,观察孤儿受体TR3及其mRNA在小鼠睾丸中的表达及细胞定位.结果表明,在小鼠睾丸中有显著量的孤儿受体TR3 mRNA和蛋白表达,其表达量在不同曲细精管有明显的差异;孤儿受体TR3蛋白主要定位于生精细胞,其mRNA在生精细胞特异表达,主要在精原细胞和发育早期的初级精母细胞表达,提示孤儿受体TR3在小鼠曲细精管精子发生的早期阶段中起着调控作用.
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