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Research progress on ocular biomarkers for the occurrence and progression of retinal vein occlusion

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Author:: No author available

Journal Title:: International Eye Science

Issue:: 12

DOI:: 10.3980/j.issn.1672-5123.2022.12.14

Key Word:: 视网膜静脉阻塞;眼部生物标记物;光学相干断层成像;缺血;视力

Abstract：视网膜静脉阻塞(RVO)是仅次于糖尿病视网膜病变(DR)的第二大常见的视网膜血管性疾病.近年研究陆续发现,一些眼部辅助检查得到的指标或征象可预示疾病的发生发展及视力结局,我们称之为眼部生物标记物(biomarker),如视网膜内层结构紊乱(DRIL)、急性黄斑旁中心中层视网膜病变(PAMM)、突出的中界膜征(p-MLM)、视网膜内高反射灶(HRF)、视网膜下液(SRF)、椭圆体带(EZ)、外界膜(ELM)及浅表毛细血管丛(SCP)与深层毛细血管丛(DCP)等.本文就RVO的眼部生物标记物进行综述,希望通过这些指标从多维度观察RVO的发生及发展,对RVO预后判断提供指导,更全面地认识该疾病,并避免严重的视力结局.

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