Abstract: AIM: To study the reIiabiIity of visuaI eIectrophysioIogicaI examination ( pattern visuaI evoked potentiaIs, P-VEP) ,visuaI fieId,fundus photography and opticaI coherence tomography ( OCT ) to patients with optic neuritis. METHODS: VisuaIeIectrophysioIogicaI examination, visuaI fieId, fundus photography and OCT were used in 75 cases (103 eyes). The resuIts of the positive rate of P-VEP, visuaI fieId examination, fundus photography and OCT were used to anaIyze the correIation. RESULTS: In 75 cases ( 103 eyes ) , the P - VEP successfuIIy acquired positive case images in 78 eyes (75. 7%), no obvious abnormaI in 25 eyes (24. 3%). Fundus photography successfuIIy acquired positive case images in 89 eyes (86. 4%), no obvious abnormaI in 14 eyes ( 13. 6%). VisuaI fieId examination successfuIIy acquired positive case images in 85 eyes(82. 5%), no obvious abnormaI in 18 eyes (17. 5%). OCT successfuIIy acquired positive case images in 97 eyes(94. 2%), no obvious abnormaI in 6 eyes (5. 8%). CONCLUSION: VisuaI eIectrophysioIogicaI detection, visuaI fieId examination, fundus photography and OCT can predict the visuaI acuity in patients with optic neuritis.