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Biocompatibility of intraocular lens cytokine in aqueous humor

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Author:: No author available

Journal Title:: International Eye Science

Issue:: 11

DOI:: 10.3980/j.issn.1672-5123.2014.11.18

Key Word:: 人工晶状体;生物相容性;房水;细胞因子;intraocular lens;biocompatibility;aqueous humor;cytokine

Abstract： Intraocular lens ( IOL) implantation is the major method to replace the cataract lens. How to improve the biocompatibility of IOL has been the focus of current research. Major reactions after the IOL implantation include endophthalmitis, corneal endothelial edema, iritis, uveitis, and posterior capsule opacification, etc. At cellular level, macrophages, monocytes, fibroblasts and lens epithelial cells can be detected on the surface of IOL. Their adhesion, proliferation migration, and transformation may be induced by the operation related cytokines released into the aqueous humor. Detailed analysis of cytokines profile after IOL implantation may be beneficial to explore the mechanism of posterior capsule opacification.

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