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The clinical value of thrombelastography in diagnosis and treatment of acute traumatic coagulopathy

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Author:: No author available

Journal Title:: Chinese Journal of Emergency Medicine

Issue:: 8

DOI:: 10.3760/cma.j.issn.1671-0282.2016.08.026

Key Word:: 血栓弹力图;急性创伤性凝血病;诊疗价值;Acute traumatic coagulopathy;Thrombelastography;Clinical value

Abstract： Acute traumatic coagulopathy (ATC) is one of coagulopathy induced by severe trauma in the early phase of trauma.It is always with high morbidity,mortality and multiple organ failure.Early diagnosis and treatment is the main content of trauma surgery in the department of emergency and the key to reduce mortality.Thrombelastography (TEG) can comprehensively assess the different stages of coagulation,early diagnose disturbance of blood coagulation and guide the goal-directed therapy with low complications,mortality and medical costs.TEG has been widely used in the operation of cardiac surgery,liver transplantation and trauma surgery to monitor coagulation and guide therapy.This paper mainly reviews the clinical value of thrombelastography in diagnosis and treatment of acute traumatic coagulopathy.

Reference

[1]陈冠伊,欧阳锡林,吴靖辉,等.血栓弹力图与常规凝血四项评价临床患者凝血功能的对比研究[J].2015,(2).
[2]王勇强,姚芳超,王兵.多器官功能障碍综合征[J].2015,(8).
[3]曹兴华,张晓婷,李清.血栓弹力图指导下脊柱侧凸手术最佳输血策略的建立[J].2016,(2).
[4].International normalized ratio as a predictor of mortality in trauma patients in India[J].2014,5(3).
[5]骆继业,陈晓兵,刘克喜,等.血栓弹力图在指导脓毒症患者肝素应用中的意义[J].2015,(10).
[6].Progress in research into the genes associated with venous thromboembolism[J].2015,6(2).
[7]张娟娟,王少华,虞文魁,等.猪创伤失血性休克模型凝血功能的变化[J].2015,(5).
[8]蔡海英,叶立刚,徐善祥,等.血栓弹力图在严重多发伤患者中的初步应用[J].2011,(12).
[9]尹文,李俊杰.急性创伤性凝血病的研究进展[J].2014,(3).
[10]刘先华,夏鹄.脓毒症患者凝血功能异常与预后的关系[J].2015,(6).
[11]Davenport R,Pearse R,De'Ath H,etc.Functional definition and characterization of acute traumatic coagulopathy.[J].2011,39(12).
[12]Montalti, Roberto,Bianchini, Marcello,Villa, Erica,etc.Thrombelastography-Guided Blood Product Use Before Invasive Procedures in Cirrhosis With Severe Coagulopathy: A Randomized, Controlled Trial[J].2016,63(2).
[13]Gonzalez, Eduardo,Moore, Ernest E.,Moore, Hunter B.,etc.Goal-directed Hemostatic Resuscitation of Trauma-induced Coagulopathy A Pragmatic Randomized Clinical Trial Comparing a Viscoelastic Assay to Conventional Coagulation Assays[J].2016,263(6).
[14]Cap, A.,Hunt, B. J..The pathogenesis of traumatic coagulopathy[J].2015,70(Suppl.1).
[15]Johansson PI,Ostrowski SR.Acute coagulopathy of trauma: balancing progressive catecholamine induced endothelial activation and damage by fluid phase anticoagulation.[J].2010,75(6).
[16]Johansson,P.I..Coagulation monitoring of the bleeding traumatized patient[J].2012,25(2).
[17]Seeberger,M.D.,Tanaka,K.A.,Bolliger,D..Principles and Practice of Thromboelastography in Clinical Coagulation Management and Transfusion Practice[J].2012,26(1).
[18]Wade,C.E.,Matijevic,N.,Cotton,B.A.,etc.Hyperfibrinolysis at admission is an uncommon but highly lethal event associated with shock and prehospital fluid administration[J].2012,73(2).
[19]Niles SE,McLaughlin DF,Perkins JG,etc.Increased mortality associated with the early coagulopathy of trauma in combat casualties.[J].2008,64(6).
[20]Stensballe,J.,Ostrowski,S.R.,Johansson,P.I..Viscoelastic guidance of resuscitation[J].2014,27(2).
[21]Frith,D.,Goslings,J.C.,Gaarder,C.,etc.Definition and drivers of acute traumatic coagulopathy: Clinical and experimental investigations[J].2010,8(9).
[22]Miroslav Durila,Martin Malošek.Rotational thromboelastometry along with thromboelastography plays a critical role in the management of traumatic bleeding[J].2014,32(3).
[23]Karon, B. S..Why is everyone so excited about thromboelastrography (TEG)?[J].2014,436(1).
[24]Donat R Spahn,Bertil Bouillon,Vladimir Cerny,etc.Management of bleeding and coagulopathy following major trauma: an updated European guideline[J].2013,17.
[25]Herbert, Sch?chl,Ulrike, Nienaber,Georg, Hofer,etc.Goal-directed coagulation management of major trauma patients using thromboelastometry (ROTEM)-guided administration of fibrinogen concentrate and prothrombin complex concentrate.[J].2010,14(2).
[26]Arash, Afshari,Anne, Wikkels,Jesper, Brok,etc.Thrombelastography (TEG) or thromboelastometry (ROTEM) to monitor haemotherapy versus usual care in patients with massive transfusion.[J].2011,(3).
[27]Weber,C.F.,G?rlinger,K.,Meininger,D.,etc.Point-of-care testing: A prospective, randomized clinical trial of efficacy in coagulopathic cardiac surgery patients[J].2012,117(3).
[28]Chapman,M.P.,Moore,E.E.,Ramos,C.R.,etc.Fibrinolysis greater than 3; is the critical value for initiation of antifibrinolytic therapy[J].2013,75(6).
[29]Katharine, Ker,Phil, Edwards,Pablo, Perel,etc.Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis.[J].2012,344.
[30]Maegele,M.,Spinella,P.C.,Sch?chl,H..The acute coagulopathy of trauma: Mechanisms and tools for risk Stratification[J].2012,38(5).
[31]Hideo, Wada,Takeshi, Matsumoto,Yoshiki, Yamashita.Diagnosis and treatment of disseminated intravascular coagulation (DIC) according to four DIC guidelines.[J].2014,2(1).
[32]Atkins,E.,Easley,K.A.,Pereira,G.,etc.Coagulopathy is prevalent and associated with adverse outcomes in transfused pediatric trauma patients[J].2012,160(2).
[33]Moeller AM,Wikkelsoe AJ,Afshari A,etc.Monitoring patients at risk of massive transfusion with Thrombelastography or Thromboelastometry: a systematic review.[J].2011,55(10).
[34]White NJ,Brophy D,Martin EJ.Coagulopathy and traumatic shock: characterizing hemostatic function during the critical period prior to fluid resuscitation.[J].2010,81(1).
[35]Floccard,B.,Rugeri,L.,Faure,A.,etc.Early coagulopathy in trauma patients: An on-scene and hospital admission study[J].2012,43(1).