You Position: Home > Paper
Risk factors influencing prognosis of patients undergoing primary retroperitoneal tumor surgery
( views:10, downloads:0 )
- Author:
- No author available
- Journal Title:
- World Chinese Journal of Digestology
- Issue:
- 9
- DOI:
- 10.11569/wcjd.v29.i9.461
- Key Word:
- 原发性腹膜后肿瘤;预后;生存率;危险因素;首发症状;肿瘤分化
Abstract： 背景 原发性腹膜后肿瘤多为恶性肿瘤,其病因多种多样.分级、切除范围和肿瘤完整性等参数已被证明影响预后.目的 探索影响原发性腹膜后肿瘤手术患者术后生存的危险因素.方法 73例腹膜后肿瘤根治性手术的患者分为无瘤生存组(47例)、复发死亡组(26例).收集并分析影响患者术后无瘤生存的因素,包括年龄、肿瘤长径、淋巴结转移、首发症状、肿瘤类型、肿瘤分化程度以及是否合并其他系统疾病等.结果 原发性腹膜后肿瘤术后5年无瘤生存率为64.4％(47/73).对影响原发性腹膜后肿瘤术后无瘤生存率的因素进行单因素分析结果显示:年龄(P＜0.05),肿瘤长径(P＜0.05),淋巴结转移(P＜0.05),首发症状(P＜0.05),肿瘤类型(P＜0.05),肿瘤分化程度(P＜0.05)共6项因素与腹膜后肿瘤术后无瘤生存率相关.多因素Cox回归分析结果提示首发症状(P＜0.05)以及肿瘤类型(P＜0.05)影响腹膜后肿瘤患者术后无瘤生存率的独立危险因素.结论 首发症状以及肿瘤类型是影响腹膜后肿瘤患者术后无瘤生存率的关键.
- [1]陈锐,吴涵潇,余永伟,等.腹膜后占位的病理诊断--单中心大样本腹膜后占位分析[J].2020,(7).
- [2]辛星.原发性盆腔腹膜后肿瘤的诊治进展[J].2013,(2).
- [3]Myung K, Kim,Chang M, Im,Sang H, Oh,etc.Unusual presentation of right-side accessory spleen mimicking a retroperitoneal tumor.[J].2008,15(8).
- [4]Park James O.,Qin Li-Xuan,Prete Francesco P.,etc.Predicting Outcome by Growth Rate of Locally Recurrent Retroperitoneal Liposarcoma[J].2009.
- [5]Pedro, Le?o,Sónia, Vila?a,Mário, Oliveira,etc.Giant recurrent retroperitoneal liposarcoma initially presenting as inguinal hernia: Review of literature.[J].2012,3(3).
- [6]Lewis Jonathan J.,Leung Denis,Woodruff James M.,etc.Retroperitoneal Soft-Tissue Sarcoma[J].1998.
- [7]Graves, B.,Zhang, Z.,Ding, Q.,etc.Discovery of RG7388, a potent and selective p53-MDM2 inhibitor in clinical development[J].2013,56(14).
- [8]Jean Yves Blay,Paolo Casali,Antonio Nieto,etc.Efficacy and safety of trabectedin as an early treatment for advanced or metastatic liposarcoma and leiomyosarcoma.[J].2014,10(1).
- [9]Dirk Strauss.Retroperitoneal tumours: review of management[J].2011,93(4).
- [10]Dorian Yarih, Garcia-Ortega,Oscar, Villa-Zepeda,Héctor, Martinez-Said,etc.Oncology outcomes in Retroperitoneal sarcomas: Prognostic factors in a Retrospective Cohort study.[J].2016.