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Role of regulatory B cells in autoimmune diseases of the digestive system

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Author:
No author available
Journal Title:
World Chinese Journal of Digestology
Issue:
12
DOI:
10.11569/wcjd.v28.i12.486
Key Word:
调节性B细胞;消化系统;自身免疫性疾病

Abstract´╝Ü 调节性B细胞(regulatoryB cells,Breg)作为B淋巴细胞中一种特殊的亚群,通过产生白介素(interleukin, IL)-10、IL-35、转化生长因子-β等细胞因子,参与消化系统自身免疫性疾病的免疫调节的作用,然而,Breg的表型和表面特异性抗原尚未确定,其潜在的治疗功能需要进一步研究.本文将就Breg在消化系统自身免疫性疾病中的作用进行综述.

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