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Fecal calprotectin and colorectal cancer
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- Author:
- No author available
- Journal Title:
- World Chinese Journal of Digestology
- Issue:
- 23
- DOI:
- 10.11569/wcjd.v27.i23.1436
- Key Word:
- 粪便钙卫蛋白;结直肠癌;筛查;鉴别
Abstract： 粪便钙卫蛋白(fecal calprotectin,FC)是一种由肠腔内炎性细胞分泌的生物活性蛋白,有抗微生物活性、抗感染等作用,通过其含量高低可反映肠道的炎症状态,其在炎性肠病中的作用已被应用于临床实践.近年来,关于FC在结直肠癌(colorectal cancer,CRC)中的应用研究逐渐增多,相关研究结果显示FC可用于CRC的筛查以及和其他肠道器质性疾病的鉴别,同时,FC的浓度与CRC的分期、发生部位以及手术可能有一定的相关性,但仍需要进一步通过高质量、大样本研究以明确.本文就FC在CRC中的研究进展作一综述.
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