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Enteric glial cells and gastrointestinal motility

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Author:: No author available

Journal Title:: World Chinese Journal of Digestology

Issue:: 26

DOI:: 10.11569/wcjd.v26.i26.1537

Key Word:: 肠神经胶质细胞;胃肠道运动;肠神经系统;肠道炎症

Abstract：肠神经胶质细胞(enteric glial cells,EGCs)是肠神经系统的重要组成部分,在维持胃肠道功能方面发挥着重要作用.营养和支持胃肠神经元,参与胃肠道内神经活动的整合和调节以及参与肠道炎症反应,直接或间接调节胃肠道运动功能.研究肠神经胶质细胞对胃肠神经的影响以及在肠道炎症所致胃肠道运动障碍中的作用,有助于揭示肠神经胶质细胞对胃肠道动力影响的作用机制.在临床上,EGCs具有作为多种胃肠道运动功能障碍性疾病的治疗靶点的应用前景.本文将对EGCs对胃肠道运动功能的影响进行综述.

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