Paper - WANFANG MED ONLINE

You Position: Home > Paper

Regulatory effect of Qiwei Baizhu powder on intestinal microecology in patients with dysbacteria associated diarrhea

( views:72, downloads:0 )

Author:: No author available

Journal Title:: World Chinese Journal of Digestology

Issue:: 17

DOI:: 10.11569/wcjd.v26.i17.1022

Key Word:: 七味白术散;肠道乳糖酶;肠道微生态;肠道酶活性;微生物代谢;Qiwei Baizhu powder;Intestinal lactase;Intestinal microecology;Intestinal enzyme activity;Microbial metabolism

Abstract： Diarrhea is a common clinical symptom in children. The main factor responsible for diarrhea is intestinal microecological imbalance. The effect of Qiwei Baizhu powder on infantile diarrhea is remarkable. Intestinal microecology is the hot topic in current research. It is of great significance to elucidate the curative effect of Chinese medicine and the pathogenesis of diarrhea. According to the connotation of microecology and by searching the literature, this article reviews the progress in research of intestinal microbial community structure, intestinal enzyme activity, and intestinal microbial metabolism. It is shown that Qiwei Baizhu powder can repair the intestinal mucosal barrier, inhibit the propagation of harmful bacteria in the intestine, adjust intestinal flora, and improve intestinal enzyme activity by promoting the growth of beneficial bacteria in the gut, especially the activity of intestinal lactase. Qiwei Baizhu powder can regulate the levels of enzyme activity and production. These results can be used to reveal the mechanism of diarrhea to promote the clinical application of Qiwei Baizhu powder.

Reference

[1]蒲俊安,郑淘,李灿,等.蔗糖对七味白术散治疗菌群失调腹泻小鼠肠道细菌多样性的影响[J].2017,(6).
[2]桂荣.七味白术散治疗婴幼儿腹泻102例疗效观察[J].2010,(15).
[3]吕建平,徐秀丽,付孟莉.酪酸梭菌的药理作用及临床应用[J].2010,(20).
[4]王苏莉.七味白术散治疗小儿迁延性腹泻126例临床观察[J].2007,(10).
[5]李春颖.七味白术散加味治疗抗生素相关性腹泻疗效观察[J].2010,(5).
[6]章文明,汪海峰,刘建新.乳酸杆菌益生作用机制的研究进展[J].2012,(3).
[7]彭海珍,任立红.不同年龄段婴幼儿抗生素性腹泻与乳糖不耐受的相关性研究[J].2011,(26).
[8]于卓腾,姚文,毛胜勇,等.黄豆苷元对仔猪肠道微生物区系的影响[J].2007,(1).
[9]朱婷,蔡光先,吴海,等.植物成分对肠道微生物的影响[J].2010,(18).
[10]张明发,沈雅琴.非处方药小檗碱抗腹泻作用的再评价[J].2003,(3).
[11]王原,余亮科,韩秀红,等.七味白术散治疗抗生素相关性腹泻疗效观察[J].2013,(10).
[12]王春晖,张华玲,张祺玲,等.超微七味白术散对肠道厌氧微生物代谢多样性的调控作用[J].2015,(14).
[13]吕耀龙,赵春杰,刘建军.双歧杆菌的代谢及开发前景[J].2008,(2).
[14]王锡茂,黎彧,何妙银,等.甜味剂开发的研究进展[J].2012,(5).
[15]谭周进,吴海,刘富林,等.超微七味白术散对肠道微生物及酶活性的影响[J].2012,(21).
[16]肖新云,刘又嘉,邓艳玲,等.蔗糖对七味白术散治疗菌群失调腹泻小鼠血常规的影响[J].2017,(1).
[17]孙忠信,李淑华,杨秀云.乳酸杆菌对仔猪肠道微生物的影响[J].2010,(4).
[18]鞠宝玲,宋宝辉,唐小云,等.四君子汤对肠道菌群失调小鼠的调整作用及机制研究[J].2007,(5).
[19]蒋婕,郭抗萧,龙玲,等.超微七味白术散体外抑菌作用研究[J].2013,(11).
[20]惠华英,贺璐,彭昕欣,等.抗生素所致菌群失调腹泻小鼠肠道乳糖酶活性的研究[J].2017,(9).
[21]张国民,谭周进,张熙,等.微生物对化学物质构效的影响研究进展[J].2010,(17).
[22]刘起胜,徐筱红,刘怀,等.七味白术散对菌群失调腹泻小鼠肠绒毛和隐窝的影响[J].2014,(23).
[23]柴俊,郤翠仙,张以芳.乳酸杆菌主要代谢产物种类及其特性[J].2007,(8).
[24]刘丽莎,王锐,旭日花,等.白术多糖对益生菌的促生长作用及结构分析[J].2010,(19).
[25]徐永杰,张波,张祎腾.牛蒡多糖的提取及对小鼠肠道菌群的调节作用[J].2009,(23).
[26]张翼轸,张文驹,穆青,等.人参化学成分的药理活性及其含量积累的研究进展[J].2011,(20).
[27]王茂贵.微生态调节剂在儿科临床应用的评价[J].2002,(3).
[28]曾奥,张华玲,谭周进,等.小鼠菌群失调腹泻模型的建立及超微七味白术散的疗效[J].2012,(9).
[29]郭慧玲,邵玉宇,孟和毕力格,等.肠道菌群与疾病关系的研究进展[J].2015,(2).
[30]王欢,曾奥,曹蓉,等.七味白术散调节肠道微生态的物质基础[J].2014,(13).
[31]龙承星,郭艳芳,刘娅薇,等.中药对肠道黏膜免疫保护的影响及其意义[J].2017,(35).
[32]曾奥.七味白术散对肠道微生物及酶活性的影响[D].2013.
[33]刘又嘉,肖新云,邓艳玲,等.七味白术散与酵母菌联用对菌群失调腹泻模型小鼠肠道乳酸杆菌多样性的影响[J].2016,(3).
[34]张华玲,蔡莹,谭周进,等.超微七味白术散对菌群失调腹泻小鼠肠道微生物代谢多样性的影响[J].2014,(1).
[35]谭周进,张华玲,周赛男,等.菌群失调小鼠腹泻造模及超微中药干预过程中肠道微生物的变化[J].2013,(3).
[36]Long, Chengxing,Liu, Yawei,He, Lu,etc.Bacterial lactase genes diversity in intestinal mucosa of mice with dysbacterial diarrhea induced by antibiotics.[J].2018,8(3).
[37]郭抗萧,谭周进,谢梦洲,等.超微七味白术散与酵母菌协同治疗小鼠菌群失调腹泻[J].2015,(1).
[38]郭抗萧,肖新云,刘又嘉,等.七味白术散对菌群失调腹泻小鼠肠道乳酸杆菌多样性的影响[J].2015,(6).
[39]彭昕欣.蔗糖对七味白术散治疗菌群失调腹泻小鼠肠道微生物及酶的影响[D].2015.
[40]孙必强,周英,刘卫东,等.不同剂型七味白术散对肠道菌群失调腹泻小鼠小肠黏膜上皮IL-4,IL-10,IFN-α mRNA表达的影响[J].2016,(6).
[41]张华玲,周赛男,蔡莹,等.超微七味白术散对菌群失调腹泻小鼠小肠黏膜的影响[J].2013,(1).
[42]顾岚,王叶红,胥玲.乳糖酶治疗小儿腹泻病的临床分析[J].2013,(7).
[43]Kim DH,Bae EA,Shin JE.Metabolism of ginsenoside Re by human intestinal microflora and its estrogenic effect.[J].2005,28(10).
[44]杜慧真.酶与人体健康[C].2014.
[45]王欢.七味白术散与酵母菌联用对菌群失调腹泻小鼠肠道菌群分子多样性的影响[D].2015.
[46]郭抗萧,尹抗抗,王欢,等.抗生素对小鼠菌群失调腹泻肠道菌群多样性的影响[J].2014,(3).
[47]刘起胜,刘怀,彭微,等.菌群失调腹泻抗生素造模对小鼠肠黏膜的影响[J].2015,(5).
[48]邓艳玲.七味白术散对菌群失调腹泻小鼠肠道乳糖酶活性的影响[D].2017.
[49]Cheng-Xing, Long,Lu, He,Yan-Fang, Guo,etc.Diversity of bacterial lactase genes in intestinal contents of mice with antibiotics-induced diarrhea.[J].2017,23(42).
[50]Zhu,Y.,Zheng,X.,Cong,Y.,etc.Bloating and distention in irritable bowel syndrome: The role of gas production and visceral sensation after lactose ingestion in a population with lactase deficiency[J].2013,108(9).
[51]龙承星,贺璐,郭抗萧,等.超微七味白术散与酵母菌联用对菌群失调腹泻小鼠肠道细菌多样性的影响[J].2018,(1).
[52]曹俊敏,杨雪静,张伟珍.茯苓等4种中药扶植实验小鼠肠道正常菌群生长及其机理的初步研究[J].2012,(2).
[53]Hickson M.Probiotics in the prevention of antibiotic-associated diarrhoea and Clostridium difficile infection.[J].2011,4(3).
[54].Effects of jianwei qiweibaizhusan on the intestinal microorganisms and enzyme activities[J].2013.
[55]彭红.中药制剂用甜菊甙替代蔗糖势在必行[J].1995,(3).
[56]Fernie AR,Trethewey RN,Krotzky AJ,etc.Metabolite profiling: from diagnostics to systems biology.[J].2004,5(9).
[57]郭抗萧,周赛男,谭周进,等.七味白术散对肠道酵母菌的抑促作用研究[J].2013,(27).