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Value of four protein tumor markers in colorectal cancer screening

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Author:: No author available

Journal Title:: World Chinese Journal of Digestology

Issue:: 11

DOI:: 10.11569/wcjd.v25.i11.996

Key Word:: 金属蛋白酶l组织抑制剂;转铁蛋白;M2型丙酮酸激酶;结直肠癌;筛查;Plasma tissue inhibitor of metalloproteinases-1;Transferrin;M2 pyruvate kinase;Colorectal cancer;Screening

Abstract： Colorectal cancer (CRC) is one of the common malignant tumors worldwide and the fourth most common cancer in China.In recent years the incidence of CRC is still on the rise.It is of great significance to carry out effective screening for CRC with regard to improving prognosis and reducing mortality.Among many screening methods currently available,the detection of tumor markers in feces and serum is easy to operate,inexpensive,and noninvasive,thus becoming the focus of research.In view of the great significance of tumor marker detection for CRC screening,this article discusses the value of four protein tumor markers in CRC screening,with an aim to provide a theoretical basis for their clinical use.

Reference

[1]李培龙,张欣,张义,等.博新血清肿瘤相关物质（BXTM）检测在结直肠癌诊断中的价值[J].2014,(2).
[2]梁彬,郭政东,李云慧.血清中基质金属蛋白酶-9和基质金属蛋白酶组织抑制因子-1在结直肠癌中的诊断价值[J].2012,(19).
[3]金鹏,武子涛,李爱琴,等.粪便转铁蛋白和免疫粪隐血试验在结直肠癌筛查中效能的比较[J].2012,(9).
[4]李勇,王俊江,林锋,等.联合检测肿瘤M2-PK与CEA和FOBT对结直肠癌早期发现的意义[J].2011,(6).
[5]邹雄,张晓时,孙玲,等.血清肿瘤相关物质（BXTM）检测用于肿瘤辅助早期诊断的价值[J].2004,(6).
[6]王宇,沈玉栋,雷红涛,等.免疫分析标记技术研究进展[J].2007,(10).
[7]刘瑶,田亚平.免疫标记技术的现状和发展[J].2013,(8).
[8]Christensen, Ib Jarle,Brunner, Nils,Dowell, Barry,etc.Plasma TIMP-1 and CEA as Markers for Detection of Primary Colorectal Cancer: A Prospective Validation Study Including Symptomatic and Non-symptomatic Individuals[J].2015,35(9).
[9]Kim Y C, Fung,Bruce, Tabor,Michael J, Buckley,etc.Blood-based protein biomarker panel for the detection of colorectal cancer.[J].2015,10.
[10]Wild N,Andres H,Rollinger W,etc.A combination of serum markers for the early detection of colorectal cancer.[J].2010,16(24).
[11]Mahua R, Das,Arup K, Bag,Shekhar, Saha,etc.Molecular association of glucose-6-phosphate isomerase and pyruvate kinase M2 with glyceraldehyde-3-phosphate dehydrogenase in cancer cells.[J].2016.
[12]陈万青,张思维,曾红梅,等.中国2010年恶性肿瘤发病与死亡[J].2014,(1).
[13]Yong Cheol, Kim,Jeong Ho, Kim,Dae Young, Cheung,etc.The Usefulness of a Novel Screening Kit for Colorectal Cancer Using the Immunochromatographic Fecal Tumor M2 Pyruvate Kinase Test.[J].2015,9.
[14]Zhang,D.-X.,Liu,X.-L.,Li,L.-M.,etc.Comparative analysis of tumor markers and evaluation of their predictive value in patients with colorectal Cancer[J].2012,35(3).
[15]Pox,C.P..Controversies in colorectal cancer screening[J].2014,89(4).
[16]Haug,U.,Brenner,H.,Kuhn,K.,etc.Comparison and combination of blood-based inflammatory markers with faecal occult blood tests for non-invasive colorectal cancer screening[J].2012,106(8).
[17]M R, Rahman,S H, Sheikh,I J, Lima,etc.Correlation of the Serum Level of Carcinoembryonic Antigen and Prolactin with Different Stages of Colorectal Carcinoma According to Dukes' Staging.[J].2016.
[18]K, Niewiarowska,A, Pryczynicz,V, Dymicka-Piekarska,etc.Diagnostic significance of TIMP-1 level in serum and its immunohistochemical expression in colorectal cancer patients.[J].2014,65(4).
[19]Ghanouni, Alex,Plumb, Andrew,Hewitson, Paul,etc.Patients' experience of colonoscopy in the English Bowel Cancer Screening Programme[J].2016,48(3).
[20]Ashley D, Bond,Michael D, Burkitt,David, Sawbridge,etc.Correlation between Faecal Tumour M2 Pyruvate Kinase and Colonoscopy for the Detection of Adenomatous Neoplasia in a Secondary Care Cohort.[J].2016,(1).
[21]Suresh, Sithambaram,Ida, Hilmi,Khean-Lee, Goh.The Diagnostic Accuracy of the M2 Pyruvate Kinase Quick Stool Test--A Rapid Office Based Assay Test for the Detection of Colorectal Cancer.[J].2015,10(7).
[22].Serum M2-pyruvate kinase: A promising non-invasive biomarker for colorectal cancer mass screening[J].2012,(6).
[23]张莹,冯海,吴秋平,等.胶体金免疫层析技术的研究进展[J].2015,(12).
[24]Jin-Xi Huang,Yi Zhou,Cheng-Hu Wang,etc.Tumor M2-pyruvate kinase in stool as a biomarker for diagnosis of colorectal cancer: A meta-analysis.[J].2014,10(2).
[25]Kim YC Fung,Edouard Nice,Ilka Priebe,etc.Colorectal cancer biomarkers: To be or not to be? Cautionary tales from a road well travelled[J].2014,(4).
[26]Ji-Gui Chen,Juan Cai,Huan-Lei Wu,etc.Colorectal cancer screening: Comparison of transferrin and immuno fecal occult blood test[J].2012,(21).
[27]张慧,李平原,韩路英.MMP-11及TIMP-1在结直肠癌组织中的表达及意义[J].2014,(2).
[28]Stine Buch Thorsen,Martin Lundberg,Andrea Villablanca,etc.Detection of serological biomarkers by proximity extension assay for detection of colorectal neoplasias in symptomatic individuals[J].2013,11.
[29]Carolin Tonus,Markus Sellinger,Konrad Koss,etc.Faecal pyruvate kinase isoenzyme type M2 for colorectal cancer screening: A meta-analysis[J].2012,(30).
[30]Leen,R.,Seng-Lee,C.,Holleran,G.,etc.Comparison of faecal M2-PK and FIT in a population-based bowel cancer screening cohort[J].2014,26(5).
[31]Zhao,X.,Wang,Y.,Li,Y.,etc.Evaluating the significance of expression of CEA mRNA and levels of CEA and its related proteins in colorectal cancer patients[J].2014,109(5).
[32]Yan-Rong Wang,Jian-Xia Yan,Li-Na Wang.The diagnostic value of serum carcino-embryonic antigen, alpha fetoprotein and carbohydrate antigen 19-9 for colorectal cancer.[J].2014,10(3).
[33]Erwin T. Waas,Thijs Hendriks,Roger M. L. M. LommeTheo Wobbes.Plasma Levels of Matrix Metalloproteinase-2 and Tissue Inhibitor of Metalloproteinase-1 Correlate With Disease Stage and Survival in Colorectal Cancer Patients[J].2005,48(4).
[34]吕忠船,陈红兵,姜立新,等.应用肿瘤标志物进行筛查结直肠癌的方法的建立及评价[J].2013,(10).