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Clinicopathologic features of esophageal collision carcinoma: Analysis of five cases
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- Author:
- No author available
- Journal Title:
- World Chinese Journal of Digestology
- Issue:
- 9
- DOI:
- 10.11569/wcjd.v24.i9.1417
- Key Word:
- 食管碰撞癌;免疫组织化学;诊断;鉴别;Esophageal collision carcinoma;Immunohistochemistry;Diagnosis;Differential
Abstract： 目的:探讨食管碰撞癌的临床病理学特征、病理诊断、免疫表型及鉴别诊断.方法:收集漯河市中心医院及漯河市第五人民医院2008-01/2015-12经常规HE及免疫组织化学染色确诊的食管碰撞癌5例,同期食管癌1412例的临床和病理学资料,结合文献,进行回顾性分析.结果:食管碰撞癌是一种罕见的肿瘤组合类型,高发年龄＞65岁,男性高发;好发部位为食管中段、食管与贲门交界处;病理组织学特点以鳞状细胞癌碰撞腺癌、鳞状细胞癌碰撞小细胞神经内分泌癌、鳞状细胞癌碰撞平滑肌肉瘤为特点,两种碰撞肿瘤位置靠近,中间隔以非肿瘤性间质,无移行及过渡,有各自的转移途径.食管碰撞癌以鳞癌和腺癌的碰撞常见.结论:食管碰撞癌非常罕见,与一般食管癌相比,缺乏明显的特异性临床表现,术前诊断比较困难,术后病理诊断是唯一的确诊方法,因此在碰撞癌的诊断中,应充分取材,避免漏诊,以更好的指导临床的放化疗方案.
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