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Mechanisms of calcium intake in lowering serum cholesterol levels

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Author:: No author available

Journal Title:: World Chinese Journal of Digestology

Issue:: 4

DOI:: 10.11569/wcjd.v24.i4.505

Key Word:: 钙;胆固醇;机制;Calcium;Cholesterol;Mechanism

Abstract：心血管疾病(cardiovascular diseases,CVDs)已经成为全球危害人类健康生命的头号死因.平均每年有1710万人因CVDs丧命,其中,超过40％的人死于冠心病,而高胆固醇血症是引起冠心病发病率和死亡率上升的主要危险因素,并且血清胆固醇水平是冠心病发病的主要预测因素.大量研究证实,增加钙摄入可以降低或改善血浆胆固醇浓度,这对预防CVDs,特别是冠心病的发生和发展具有重大意义,本文就钙摄入降低血胆固醇水平的作用机制进行综述,涉及的内容主要包括:增加胆汁酸的排泄、干扰胆固醇吸收、抑制饱和脂肪酸的吸收、促进能量代谢、调节血1,25(OH)2D水平、影响胰岛素敏感性和控制食欲等.

Reference

[1]徐超,王晓红,王松涛,等.大豆蛋白降低大鼠血浆胆固醇机理的初步探讨[J].2002,(3).
[2]MA Ka Ying,LIANG Yin Tong,CHEN Jing Nan,etc.Dietary Calcium Decreases Plasma Cholesterol Level only in Female but not in Male Hamster Fed a High Cholesterol Diet[J].2012,(4).
[3]徐超,庞保柱,王晓红,等.大豆蛋白对人体血浆胆固醇的影响及机制探讨[J].2005,(1).
[4]王海英,孙长颢,周晓蓉,等.膳食钙降低饮食诱导肥胖大鼠体重的机制[J].2004,(9).
[5]徐超,王晓红,王松涛,等.大豆蛋白和高钙摄入对高血胆固醇模型大鼠血脂水平的影响[J].2001,(5).
[6]孙长颢,于新凤,李颖,等.膳食钙对高脂膳食大鼠血糖、血脂及激素的影响[J].2004,(2).
[7]翟凤英,何宇娜,王志宏,等.中国城乡居民膳食营养素摄入状况及变化趋势[J].2005,(3).
[8]Bell RA,Liese AD,Lawson AB,etc.Dairy, magnesium, and calcium intake in relation to insulin sensitivity: approaches to modeling a dose-dependent association.[J].2006,164(5).
[9]Lai, H.V.,Espe, M.,Jordal, A.E.O.,etc.Feed intake and brain neuropeptide Y (NPY) and cholecystokinin (CCK) gene expression in juvenile cobia fed plant-based protein diets with different lysine to arginine ratios[J].2013,165A(3).
[10]Morris KL,Zemel MB.1,25-dihydroxyvitamin D3 modulation of adipocyte glucocorticoid function.[J].2005,13(4).
[11]Soerensen,K.V.,Thorning,T.K.,Astrup,A.,etc.Effect of dairy calcium from cheese and milk on fecal fat excretion, blood lipids, and appetite in young men[J].2014,99(5).
[12]Talya Waldman,Raheleh Sarbaziha,C. Noel Bairey Merz,etc.Calcium Supplements and Cardiovascular Disease: A Review[J].2015,9(4).
[13]Chai,W.,Cooney,R.V.,Franke,A.A.,etc.Effects of calcium and vitamin D supplementation on blood pressure and serumlipids and carotenoids: A randomized, double-blind, placebo-controlled, clinicaltrial[J].2013,23(9).
[14]Xin,J.,Zhang,R.,Li,D.,etc.S100A16 mediation of weight gain attenuation induced by dietary calcium[J].2012,61(2).
[15]Michael B. Zemel.Nutritional and endocrine modulation of intracellular calcium: Implications in obesity, insulin resistance and hypertension[J].1998,188(1).
[16]Asemi,Z.,Karamali,M.,Esmaillzadeh,A..Effects of calcium-vitamin D co-supplementation on glycaemic control, inflammation and oxidative stress in gestational diabetes: A randomised placebo-controlled trial[J].2014,57(9).
[17]Zemel,MB,Shi,H,Greer,B,etc.Regulation of adiposity by dietary calcium.[J].2000,14(9).
[18]T, Vaskonen,E, Mervaala,T, Sepp?nen-Laakso,etc.Diet enrichment with calcium and magnesium enhances the cholesterol-lowering effect of plant sterols in obese Zucker rats.[J].2001,11(3).
[19]中国营养学会, 编著.中国居民膳食营养素参考摄入量[M].2014.
[20]Shin, Song Kyoung,Kim, Mi Kyung,Lee, Young-Hoon,etc.The cross-sectional relationship between dietary calcium intake and metabolic syndrome among men and women aged 40 or older in rural areas of Korea[J].2015,9(3).
[21]Campbell P,Zemel MB,Richards J,etc.Effects of calcium and dairy on body composition and weight loss in African-American adults.[J].2005,13(7).
[22]S, Lally,D, Owens,G H, Tomkin.The different effect of pioglitazone as compared to insulin on expression of hepatic and intestinal genes regulating post-prandial lipoproteins in diabetes.[J].2007,193(2).
[23]Shi H,Norman AW,Okamura WH,etc.1alpha,25-dihydroxyvitamin D3 inhibits uncoupling protein 2 expression in human adipocytes.[J].2002,16(13).
[24]G, Andryskowski,J, Chojnowska-Jezierska,M, Broncel,etc.Effect of calcium lactate supplementation on cholesterol concentration in patients with hyperlipidaemia and previous viral hepatitis: a preliminary report.[J].1900,19(2).
[25]S M, Grundy,M A, Denke.Dietary influences on serum lipids and lipoproteins.[J].1990,31(7).
[26]Ledoux M,Anderson GH,St-Pierre S,etc.Recent developments in calcium-related obesity research.[J].2008,9(5).
[27]Zhenwu, Huang,Jie, Dong,Jing, Zeng,etc.[Changes of serum lipids after soy isoflavone and calcium supplementation in postmenopausal Chinese women with different ER-beta genotypes].[J].2011,40.
[28]Madhumita, Premkumar,Tarulata, Sable.Obesity, dyslipidemia and cholesterol gallstone disease during one year of Antarctic residence.[J].2012,12.
[29]Gholamreza, Veghari,Mehdi, Sedaghat,Hamidraza, Joshghani,etc.Obesity and risk of hypercholesterolemia in Iranian northern adults.[J].2013,9(1).
[30]JaeHee,Kim.Relationship between milk and calcium intake and lipid metabolism in female patients with type 2 diabetes.[J].2013,54.
[31]M A, Denke,M M, Fox,M C, Schulte.Short-term dietary calcium fortification increases fecal saturated fat content and reduces serum lipids in men.[J].1993,123(6).
[32]Nobre, J. L.,Lisboa, P. C.,Silva Lima, N. da,etc.Calcium supplementation prevents obesity, hyperleptinaemia and hyperglycaemia in adult rats programmed by early weaning.[J].2012,107(7).
[33]Chu,X.,Liu,L.,He,Y.,etc.Calcium supplementation increases circulating cholesterol by reducing its catabolism via GPER and TRPC1-dependent pathway in estrogen deficient women[J].2013,168(3).
[34]Carvalho DC,Sanjuliani AF,Ferreira Tda S,etc.Dietary calcium intake and its relationship with adiposity and metabolic profile in hypertensive patients.[J].2011,27(6).
[35]So-Young, Bu,Myung-Hwa, Kang,Eun-Jin, Kim,etc.Dietary Intake Ratios of Calcium-to-Phosphorus and Sodium-to-Potassium Are Associated with Serum Lipid Levels in Healthy Korean Adults.[J].2012,17.