Paper - WANFANG MED ONLINE

You Position: Home > Paper

Pregnancy related problems in inflammatory bowel disease

( views:21, downloads:0 )

Author:: No author available

Journal Title:: World Chinese Journal of Digestology

Issue:: 3

DOI:: 10.11569/wcjd.v24.i3.382

Key Word:: 炎症性肠病;生育力;妊娠;哺乳;分娩方式;Inflammatory bowel disease;Fertility;Pregnancy;Breast feeding;Delivery

Abstract：炎症性肠病(inflammatory bowel disease,IBD)好发于育龄期,女性患者在妊娠,分娩期可出现IBD活动或暴发加剧,使患者病情复杂化.IBD对妊娠结局的影响及育龄患者对药物或手术治疗干预的潜在需求,使得IBD患者妊娠问题的关注度逐年提高,患者也往往就生育,妊娠及母乳喂养问题进行咨询.本文就IBD患者的生育,妊娠及药物安全性进行探讨,建议临床医生指导患者消除恐惧心理,于静止期计划受孕,接受风险最小的个体化治疗,以获得良好的妊娠结局.

Reference

[1]Shinya Ito,Aviva Blajchman,Megan Stephenson,etc.Prospective follow-up of adverse reactions in breast-fed infants exposed to maternal medication[J].1993,168(5).
[2]Loza E,Carmona L,Martinez Lopez JA.Systematic review on the safety of methotrexate in rheumatoid arthritis regarding the reproductive system (fertility, pregnancy, and breastfeeding).[J].2009,27(4).
[3]Dignass A,Kolacek S,Mackillop L,etc.European evidenced-based consensus on reproduction in inflammatory bowel disease.[J].2010,4(5).
[4]Kasper Ørding Olsen,Svend Juul,Ina Berndtsson,etc.Ulcerative colitis: Female fecundity before diagnosis, during disease, and after surgery compared with a population sample[J].2002,122(1).
[5]Koren G,Bar-Oz B,Einarson T,etc.Pregnancy outcome after cyclosporine therapy during pregnancy: a meta-analysis.[J].2001,71(8).
[6]Cohen-Kerem R,Berkovitch M,Braunstein R,etc.Pregnancy outcome of women exposed to azathioprine during pregnancy.[J].2007,79(10).
[7]Naik,A.S.,Perera,L.P.,Zadvornova,Y.,etc.Impact of pregnancy on health-related quality of life of patients with inflammatory bowel disease[J].2012,13(9).
[8]Piccinni MP,Maggi E,Scaletti C,etc.Role of hormone-controlled Th1- and Th2-type cytokines in successful pregnancy.[J].2000,109(1).
[9]AWaljee,JWaljee,A MMorris,etc.Threefold increased risk of infertility: a meta-analysis of infertility after ileal pouch anal anastomosis in ulcerative colitis[J].2006,55(11).
[10]G G Birnie,T I McLeod,G Watkinson.Incidence of sulphasalazine-induced male infertility.[J].1981,22(6).
[11]Heather A, Boyd,Saima, Basit,Maria C, Harps?e,etc.Inflammatory Bowel Disease and Risk of Adverse Pregnancy Outcomes.[J].2015,10.
[12]M C, Di Paolo,O A, Paoluzi,R, Pica,etc.Sulphasalazine and 5-aminosalicylic acid in long-term treatment of ulcerative colitis: report on tolerance and side-effects.[J].2001,33(7).
[13]Moretti,M.E.,Hutson,J.R.,Matlow,J.N.,etc.The fetal safety of thiopurines for the treatment of inflammatory bowel disease in pregnancy[J].2013,33(1).
[14]Uma Mahadevan,William J. Sandborn,De–Kun Li,etc.Pregnancy Outcomes in Women With Inflammatory Bowel Disease: A Large Community-Based Study From Northern California[J].2007,133(4).
[15]Granath F,Ekbom A,Stephansson O,etc.Crohn's disease is a risk factor for preterm birth.[J].2010,8(6).
[16]F. Agret,J. Cosnes,Z. Hassani,etc.Impact of pregnancy on the clinical activity of Crohn's disease[J].2005,21(5).
[17]Kallen B,Cleary BJ.Early pregnancy azathioprine use and pregnancy outcomes.[J].2009,85(7).
[18]Rahimi R,Abdollahi M,Nikfar S,etc.Pregnancy outcome in women with inflammatory bowel disease following exposure to 5-aminosalicylic acid drugs: a meta-analysis.[J].2008,25(2).
[19]Arno C. Gutleb,Margaret Saunders,Janneche U. Skaare,etc.Reproductive and Developmental Toxicity of Phthalates[J].2009,12(3).
[20]O'Toole, Aoibhlinn,Nwanne, Ogochukwu,Tomlinson, Tracy.Inflammatory Bowel Disease Increases Risk of Adverse Pregnancy Outcomes: A Meta-Analysis[J].2015,60(9).
[21]Cadiot G,Seksik P,Nisard A,etc.Pregnancy outcome in patients with inflammatory bowel disease treated with thiopurines: cohort from the CESAME Study.[J].2011,60(2).
[22]van der Woude, C. J.,Ardizzone, S.,Bengtson, M. B.,etc.The Second European Evidenced-Based Consensus on Reproduction and Pregnancy in Inflammatory Bowel Disease[J].2015,9(2).
[23]Homar,V.,Grosek,S.,Battelino,T..High-dose methylprednisolone in a pregnant woman with Crohn's disease and adrenal suppression in her newborn[J].2008,94(4).
[24]Berdah,S.,Lefevre,J.H.,Beyer-Berjot,L.,etc.A total laparoscopic approach reduces the infertility rate after ileal pouch-anal anastomosis: A 2-center study[J].2013,258(2).
[25]J Cornish,E Tan,J Teare,etc.A meta-analysis on the influence of inflammatory bowel disease on pregnancy[J].2007,56(6).
[26]Sarah Glover,David T Rubin,Maria T Abreu,etc.Placental transfer of anti-tumor necrosis factor agents in pregnant patients with inflammatory bowel disease.[J].2013,11(3).
[27]Nielsen MJ,Christensen LA,Fallingborg JF,etc.Azathioprine treatment during lactation.[J].2008,28(10).
[28]Guy D. Eslick,Henry Murray,Alexander A. Simring,etc.The effects of azathioprine on birth outcomes in women with inflammatory bowel disease (IBD)[J].2011,5(3).
[29]Riis, Lene,Vind, Ida,Politi, Patrizia,etc.Does Pregnancy Change the Disease Course? A Study in a European Cohort of Patients with Inflammatory Bowel Disease.[J].2006,101(7).
[30]L, Ost,G, Wettrell,I, Bj?rkhem,etc.Prednisolone excretion in human milk.[J].1985,106(6).