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Comparison between H pylori eradication rates of two moxifloxacin-based triple therapies
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- Author:
- No author available
- Journal Title:
- WORLD CHINESE JOURNAL OF DIGESTOLOGY
- Issue:
- 25
- DOI:
- 10.3969/j.issn.1009-3079.2008.25.018
- Key Word:
- 幽门螺杆菌;莫西沙星;7d三联疗法
Abstract： 目的:比较两种以莫西沙星为基础的7 d三联疗法对H pylori感染的根除率.方法:采用平行对照实验设计,52例Hpylori(+)患者分为2组,EMT组:埃索美拉唑20mg bid、莫西沙星0.4 g qd、替硝唑0.5 gbid;RMA组:枸橼酸铋雷尼替丁0.4 g bid、莫西沙星0.4 g qd、阿莫西林1.0 g bid,治疗7 d,治疗结束4 wk后通过13C-UBT检查Hpylori是否根除.结果:EMT组Hplori根除率为83.3%,RMA组根除率为79.4%.两组之间H pylori根除率没有显著性差异(x2=0.117,P=0.521).结论:以莫西沙星为基础的7 d三联疗法是可供选择的H pylori根除方案.
- [1]孟静娟.新抗生素莫西沙星国内外研究应用最新进展[J].2007,(5).
- [2]胡明礼.国内莫西沙星不良反应文献分析[J].2007,(4).
- [3]Cheon JH,Kim N,Lee DH,etc.Efficacy of moxifloxacin-based triple therapy as second-line treatment for Helicobacter pylori infection[J].2006,11(1).
- [4]Park YS,Kim JS,Song IS,etc.Institutional difference of antibiotic resistance of Helicobacter pylori strains in Korea.[J].2006,40(8).
- [5]Lascols C,Soussy CJ,Cattoir V,etc.Update on fluoroquinolone resistance in Helicobacter pylori: new mutations leading to resistance and first description of a gyrA polymorphism associated with hypersusceptibility[J].2007,29(4).
- [6]Higashi H,Yamakawa A,Yamazaki S,etc.Distinct Diversity of vacA, cagA, and cagE Genes of Helicobacter pylori Associated with Peptic Ulcer in Japan.[J].2005,43(8).
- [7]Ricci C,Morini S,Hassan C,etc.13C-urea breath test values and Helicobacter pylori eradication.[J].2008,53(2).
- [8]Martin IT,Rincon MR,Sanchez JE,etc.Susceptibility of Helicobacter pylori to mupirocin, oxazolidinones, quinupristin/dalfopristin and new quinolones.[J].2000,46(2).
- [9]Barik A, Salih,Fatih M, Ipek.Global research on Helicobacter pylori.[J].2007,52(1).