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Integrons and gene cassettes in antibiotic-resistant Shigella

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Author:: No author available

Journal Title:: WORLD CHINESE JOURNAL OF DIGESTOLOGY

Issue:: 8

DOI:: 10.3969/j.issn.1009-3079.2007.08.011

Key Word:: 基因盒;整合子;志贺菌;耐药

Abstract：随着抗生素的广泛应用,志贺菌的耐药特别是多重耐药问题日趋严重.具有捕获及表达外来基因能力的整合子(integron)系统作为新的细菌耐药机制,正越来越受关注.根据整合酶int Ⅰ的不同,整合子可分为6类.其中1,2,3类整合子研究较多,并已被证明与细菌的耐药性有关.最近研究表明,2类整合子是志贺菌中最常见的整合子.本文就基因盒-整合子系统的概念、结构及与志贺菌耐药相关性等进行综述.

Reference

[1]Mukhopadhyay C,Shivananda PG,Wilson G,etc.Isolation & antimicrobial susceptibility of Shigella from patients with acute gastroenteritis in Western Nepal.[J].2006,123(2).
[2]Mora GC,Flores O,Farfan M,etc.Genetic analysis of antibiotic-resistance determinants in multidrug-resistant Shigella strains isolated from Chilean children.[J].2005,133(1).
[3]DeLappe N,Corbett Feeney G,O'Halloran F,etc.Antimicrobial resistance and genetic diversity of Shigella sonnei isolates from western Ireland, an area of low incidence of infection.[J].2003,41(5).
[4]D, Mazel,B, Dychinco,V A, Webb,etc.A distinctive class of integron in the Vibrio cholerae genome.[J].1998,280.
[5]Rawlinson WD,McIver CJ,Karagiannis T,etc.Epidemic strains of Shigella sonnei biotype g carrying integrons.[J].2002,40(4).
[6]Ashkenazi S,Kazaronovski V,Samra Z,etc.Growing antimicrobial resistance of Shigella isolates.[J].2003,51(2).
[7]Seol SY,Cho DT,Oh JY,etc.Changes in patterns of antimicrobial susceptibility and integron carriage among Shigella sonnei isolates from southwestern Korea during epidemic periods.[J].2003,41(1).
[8]Nordmann P,Heritier C,Tolun V,etc.Emergence of oxacillinase-mediated resistance to imipenem in Klebsiella pneumoniae.[J].2004,48(1).
[9]Walsh TR.Combinatorial genetic evolution of multiresistance[J].2006,9(5).
[10]Desmarchelier PM,Gobius KS,Pemberton JM,etc.Isolation and Characterization of Integron-Containing Bacteria without Antibiotic Selection.[J].2004,48(3).
[11]Y, Arakawa,M, Murakami,K, Suzuki,etc.A novel integron-like element carrying the metallo-beta-lactamase gene blaIMP.[J].1995,39.
[12]F, Gallardo,J, Ruiz,S M, Soto,etc.[Different antibiotic resistance mechanisms associated with integrons in clinical isolates of Salmonella typhimurium].[J].2003,16(4).
[13]Anne O. Summers.GENETIC LINKAGE AND HORIZONTAL GENE TRANSFER, THE ROOTS OF THE ANTIBIOTIC Multi-RESISTANCE PROBLEM[J].2006,17(2).
[14]Montserrat, Sabaté,Guillem, Prats.[Structure and function of integrons].[J].1900,20.
[15]Mazel D.,Rowe-Magnus DA.,Guerout AM..Bacterial resistance evolution by recruitment of super-integron gene cassettes[J].2002,43(6).
[16]Duran C,Levine MM,Fulla N.Surveillance for Antimicrobial Resistance Profiles Among Shigella Species Isolated from a Semirural Community in the Northern Administrative Area of Santiago, Chile.[J].2005,72(6).
[17]Yalcin SS,Gur D,Gokturk B,etc.Shigella antibiotic resistance in central Turkey: comparison of the years 1987-1994 and 1995-2002.[J].2005,40(3).
[18]Mazel D.Integrons: agents of bacterial evolution[J].2006,4(8).
[19]H. Harbottle,S. Thakur,S. Zhao,etc.Genetics of Antimicrobial Resistance[J].2006,17(2).
[20]Navia MM,Vila J,Ruiz J.Molecular characterization of the integrons in S higella strains isolated from patients with traveler's diarrhea.[J].2004,48(3).
[21]Seol SY,Lee JC,Choi CH,etc.Prevalence of dfr genes associated with integrons and dissemination of dfrA17 among urinary isolates of Escherichia coli in Korea.[J].2004,53(3).
[22]Bouvier M,Mazel D,Demarre G.Integron cassette insertion: a recombination process involving a folded single strand substrate.[J].2005,24(24).
[23]Ploy MC,Lambert T,Couty JP,etc.Integrons: an antibiotic resistance gene capture and expression system.[J].2000,38(6).
[24]Jeannette, Mu?oz,Helia, Bello,Mariana, Domínguez,etc.[Integrons and antimicrobial resistance gene cassettes in Shigella flexneri strains].[J].2003,131(7).
[25]Sharma M,Vermani A,Dogra A,etc.Re-emergence of multi-drug resistant Shigella dysenteriae with added resistance to ciprofloxacin in north India & their plasmid profiles.[J].2005,122(4).
[26]Mammina C,Pontello M,Dal Vecchio A,etc.Identification of Shigella sonnei biotype g isolates carrying class 2 integrons in Italy (2001 to 2003).[J].2005,43(5).
[27]Leclercq R,Depardieu F,Podglajen I,etc.Modes and modulations of antibiotic resistance gene expression.[J].2007,20(1).
[28]Iversen J,Srijan A,Dalsgaard A,etc.Characterization of Antimicrobial Resistance, Plasmids, and Gene Cassettes in Shigella spp. from Patients in Vietnam.[J].2003,9(Suppl.1).
[29]Schmitz FJ,Fluit AC.Resistance integrons and super-integrons.[J].2004,10(4).
[30]Gerardo, González,Sergio, Mella,Raúl, Zemelman,etc.[Integrons and resistance gene cassettes: structure and role against antimicrobials].[J].2004,132(5).