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Comparison between effects of ligation and sclerotherapy in treatment of esophageal variceal bleeding after liver cirrhosis: a meta-analysis
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- Author:
- No author available
- Journal Title:
- WORLD CHINESE JOURNAL OF DIGESTOLOGY
- Issue:
- 17
- DOI:
- 10.3969/j.issn.1009-3079.2006.17.010
- Key Word:
- 硬化;套扎;肝硬化;食管静脉曲张出血;荟萃分析
Abstract： 目的:对套扎疗法与硬化疗法治疗肝硬化食管静脉曲张出血的疗效进行系统评价.方法:通过Medline、EMBase和中国期刊全文数据库检索1985-01/2005-11发表的有关硬化疗法与套扎疗法治疗肝硬化食管静脉曲张出血相关文献,并采用RevMan4.2.8进行Meta分析.结果:按照入选标准,有7项前瞻性随机对照临床试验纳入.Meta分析结果显示,硬化疗法在治疗肝硬化食管静脉曲张中的再出血率高于套扎疗法(RR=1.32,95%CI:1.10-1.57,(P＜0.05);而在降低死亡率方面二者相似(RR=1.24,95%CI:0.99-1.55,P＞0.05).结论:套扎疗法较硬化疗法在治疗肝硬化食管静脉曲张中能更好的预防再出血,在降低死亡率方面无差异.
- [1]曾民德.食管胃静脉曲张出血的预测及其治疗对策[J].1998,(2).
- [2]刘诗,许军英,侯晓华.内镜结扎治疗食管静脉曲张破裂出血的长期疗效观察[J].2000,(4).
- [3]刘德良,霍继荣,吴小平,等.套扎与硬化治疗食管静脉曲张出血的临床对比研究[J].1999,(2).
- [4]D, Baroncini,G L, Milandri,D, Borioni,etc.A prospective randomized trial of sclerotherapy versus ligation in the elective treatment of bleeding esophageal varices.[J].1997,29.
- [5]G V, Stiegmann,J S, Goff,P A, Michaletz-Onody,etc.Endoscopic sclerotherapy as compared with endoscopic ligation for bleeding esophageal varices.[J].1992,326(23).
- [6]G H, Lo,K H, Lai,J S, Cheng,etc.A prospective, randomized trial of sclerotherapy versus ligation in the management of bleeding esophageal varices.[J].1995,22.
- [7]A.E.S. Gimson,J.K. Ramage,M.Z. Panos,etc.Randomised trial of variceal banding ligation versus injection sclerotherapy for bleeding oesophageal varices[J].1993,342(8868).
- [8]L, Laine,H M, el-Newihi,B, Migikovsky,etc.Endoscopic ligation compared with sclerotherapy for the treatment of bleeding esophageal varices.[J].1993,119(1).