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Advance in serological tumor markers associated with gastric cancer
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- Author:
- No author available
- Journal Title:
- WORLD CHINESE JOURNAL OF DIGESTOLOGY
- Issue:
- 12
- DOI:
- 10.3969/j.issn.1009-3079.2005.12.017
- Key Word:
- No keyword available
Abstract： 胃癌是严重威胁人类健康的恶性肿瘤之一,其防治有赖于早期发现及选择合适的治疗方案,寻找特异性肿瘤标志物对以上两方面均有重要作用,其中血清学肿瘤标志物以其特殊的优势成为众多学者研究的重点.近年来学者们针对胃癌血清学肿瘤标志物,包括基因、蛋白水平,作了详细的研究.这些血清学肿瘤标志物对于胃癌的早期诊断、组织分型及判断预后等都有重要意义.本文分别叙述了基因、抗原及抗体、酶及同工酶、激素等肿瘤标志物,尤其针对当前研究的热点问题-循环DNA,总结了其定量及定性改变的意义.文章分析了各个肿瘤标志物的基础研究及临床用途,并指出了当前胃癌血清学肿瘤标志物检测中存在的问题及可行的解决途径.
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