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Anti-tumor effect of defensins

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Author:: No author available

Journal Title:: WORLD CHINESE JOURNAL OF DIGESTOLOGY

Issue:: 6

DOI:: 10.3969/j.issn.1009-3079.2001.06.028

Key Word:: 肽类/药理学;肿瘤细胞,培养的/药物作用;肿瘤/治疗;基因疗法;细胞毒性,免疫

Abstract： @@ 当代肿瘤的治疗仍有许多问题未能解决[1,2].防御素引入肿瘤基因治疗已成为一个有前景的新途径.防御素(defensins)是存在于哺乳动物多形核中性粒细胞(polymorphonuclear neutrophils,PMN)、巨噬细胞、小肠Peneth细胞中的一组同源性很高的生物多肽类,由29～34个氨基酸残基组成,Mr3000～4000.

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