Abstract： IntroductionTrichorrhexis nodosa (TN), one of the most common hair shaft anomalies, was first identified by Samuel Wilks in 1852[1]. As either a congenital or acquired hair shaft disorder, TN is characterized by fragile and easily broken hair accompanied by frayed cortical fibers and loss of the cuticle[2]. Complete fracture of the hair shaft subsequently occurs. Moreover, hair shaft fragility may increase the risk of developing TN. Congenital TN, including trichothiodystrophy[3], argininosuccinic aciduria[4], Menkes syndrome[5] and trichohepatoenteric syndrome[6], is rare in the clinical setting. Acquired TN, which is provoked by hair injury secondary to physical or chemical trauma (usually physical trauma), is often overlooked in daily life. We herein reported a case of TN in a woman with androgenetic alopecia.