Abstract： Introduction Norwegian scabies is a rare and severe skin disorder caused by scabies mites.Severe public health problems resulted from Norwegian scabies outbreak,had been reported due to the highly contagious characteristics[1-2].Also,severe complications such as secondary bacterial infections,severe water and electrolytic disorders,which could lead to fetal outcome,were reported recently in severe Norwegian scabies cases[3].Early diagnose may prevent scabies outbreak and longtime adverse events.However,crusted scabies may be misdiagnosed due to its various and atypical skin lesions.Here,we shared our experience on diagnosis of a patient with Norwegian scabies,who was misdiagnosed as psoriasis and eczema and treated with long term of oral prednisone and methotrexate.