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Application value of T-SPOT.TB assay in tuberculous infection-related skin diseases

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Journal Title:
International Journal of Dermatology and Venereology
Key Word:
结核,皮肤;结核;潜伏性结核;方法;γ干扰素释放试验;结核感染T细胞检测;Tuberculosis,cutaneous;Tuberculosis;Latent tuberculosis;Methods;Interferon-gamma release assay;T-SPOT.TB

Abstract´╝Ü Common laboratory assays for the diagnosis of tuberculosis include acid-fast smear,tissue culture,histopathological study,PCR,and so on.T-SPOT.TB assay,a new auxiliary laboratory method for tuberculosis diagnosis,belongs to interferon-gamma release assays,and has been more and more widely applied in clinical practice.This review summarizes the principles and characteristics of T-SPOT.TB assay,as well as its application values in diagnosing cutaneous tuberculosis,exploring the pathogenesis of tuberculous infection-related skin diseases,and in evaluating the risk of latent tuberculosis activation before medical treatments.

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