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Immunological advances in pathogenesis of psoriasis
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- Author:
- No author available
- Journal Title:
- INTERNATIONAL JOURNAL OF DERMATOLOGY AND VENEREOLOGY
- Issue:
- 4
- DOI:
- 10.3760/cma.j.issn.1673-4173.2010.04.009
- Key Word:
- 银屑病;免疫学;细胞因子类;Psoriasis;Immunology;Cytokines
Abstract： The pathogenesis of psoriasis is closely associated with immune system. Most of recent studies have suggested that psoriasis is a mixed Thl/Thl7 immunological disease. Besides dendritic cells, T cells, keratinocytes and Thl type cytokines such as interleukin (IL)-12 and IL-18, Thl7 type cytokines such as IL-23 and IL-22 also participate in the development of psoriasis. Thl7 type immune response may play an essential role in the pathogenesis of psoriasis.
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