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Regulatory effects of endothelins on melanocytes
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- Author:
- No author available
- Journal Title:
- INTERNATIONAL JOURNAL OF DERMATOLOGY AND VENEREOLOGY
- Issue:
- 1
- DOI:
- 10.3760/cma.j.issn.1673-4173.2008.01.020
- Key Word:
- 内皮缩血管肽类;黑素细胞
Abstract： 内皮素系统包括内皮素及其受体.该系统能够单独或者协同α-黑素细胞刺激素、干细胞因子和编码性别相关转录因子等信号分子调节黑素细胞的发育、分化、增殖、黑素合成、黏附和移行,并在色素沉着过度、白癜风和黑素瘤等皮肤色素障碍性疾病的发病过程中起着重要的作用.因此,深入研究内皮素系统与色素障碍性疾病的关系,以及研发选择性作用于内皮素受体的新型药物将为某些色素障碍性皮肤病的治疗提供新的思路和方法.
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