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Human herpesvirus 8 in the pathogenesis of multicentric Castleman's disease

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Author:: No author available

Journal Title:: INTERNATIONAL JOURNAL OF DERMATOLOGY AND VENEREOLOGY

Issue:: 1

DOI:: 10.3760/cma.j.issn.1673-4173.2008.01.010

Key Word:: 巨淋巴结增生;疱疹病毒8型,人;抗原,核;白细胞介素-6

Abstract：多中心Castleman病是一种罕见的通常不可治愈的淋巴结增生紊乱性疾病.其发病机制不清,但现在大多数学者认为与人疱疹病毒8型感染关系密切,并且发现HIV感染的患者较易发生多中心Castleman病,其原因可能是HIV感染的患者人疱疹病毒8的感染率增加.人疱疹病毒8型为一种DNA病毒,多中心Castleman病中可以检测到人疱疹病毒8型及其编码的基因,它们在多中心Castleman病发病机制中起到重要的作用.

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