Abstract: Spinal cord injury(SCI)is a disease with high disability and mortality rates.Conventional spinal cord MRI can be used to evaluate macrostructural changes caused by edema and hemorrhage after SCI,but it cannot clearly show the changes in microstructures such as axons and myelin after injury.Therefore,it is difficult to use conventional spinal cord MRI to objectively judge the degree and prognosis of SCI.Diffusion tensor imaging(DTI)is a non-invasive MRI technique that can reflect the changes in microstructures after SCI using the diffusion information of water molecules in tissues.The quantitative indicators and diffusion tensor tractography(DTT)can help to judge the degree of injury and the prognosis of patients,providing more objective reference information for clinical treatment decisions.This article reviews the application of DTI in SCI,aiming to understand the research status of DTI in SCI and provide reference for the research and development of DTI in SCI in the future.