Abstract： Glioma is the most common primary malignant tumor in the brain parenchyma.In 2021,the World Health Organization Central Nervous System(WHO CNS)further refined the classification of gliomas by using molecular typing for pathological grading and upgrading diagnosis,deepening the importance of molecular typing in the diagnosis and treatment of gliomas.At present,the gold standard for molecular typing diagnosis is pathological testing,but it has the disadvantages of an invasive operation,delayed diagnosis,and an expensive price.In recent years,with the development of diffusion kurtosis imaging(DKI)technology,more and more studies have shown that DKI plays an important role in the differential diagnosis,tumor grading,molecular typing,and prognostic treatment of gliomas.This article provides a review of the application of DKI technology in predicting molecular typing of gliomas,aiming to provide imaging indicators for predicting molecular typing of gliomas and precise clinical treatment of gliomas.