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Children transient pancytopenia preceding T-lineage acute lymphoblastic leukemia-one case report and review of literature
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- Author:
- No author available
- Journal Title:
- JOURNAL OF LEUKEMIA & LYMPHOMA
- Issue:
- 2
- DOI:
- 10.3760/cma.j.issn.1009-9921.2006.02.007
- Key Word:
- 急性T淋巴细胞白血病;全血细胞减少
Abstract： 目的提高对儿童急性淋巴细胞白血病前期(Pre-ALL)全血细胞减少的认识.方法报道1例伴有t(11;14)(q10;q10)易位的T细胞型Pre-ALL全血细胞减少患儿的临床特征及诊治经过,并进行文献复习.结果国内外以往报道的Pre-ALL均为B细胞型,该例患儿为T细胞型.患儿正规诱导化疗缓解后4个月出现中枢神经系统白血病(CNS-L),后骨髓复发,于缓解后9个月死亡.结论Pre-ALL的免疫表型可以为T细胞型,其临床亦符合T-ALL的特征,预后不良.
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