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基于肿瘤微环境探讨癌性疼痛络病病机的生物学基础
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- Author:
- No author available
- Journal Title:
- Journal of Anhui University of Chinese Medicine
- Issue:
- 1
- DOI:
- 10.3969/j.issn.2095-7246.2024.01.003
- Key Word:
- 络病理论;肿瘤微环境;癌性疼痛;生物学基础
Abstract： 基于络病理论,癌性疼痛的核心病机是络虚邪瘀,具体病机变化分为络气郁滞、络脉瘀阻、痰湿阻络、热毒滞络、络虚不荣.在癌性疼痛的发病机制中,肿瘤微环境发挥了重要作用.络脉及其中气血津液的具体变化引起癌性疼痛的过程与肿瘤微环境及其中发生物质转换、信息传递并产生疼痛的过程相类似.络气郁滞与神经内分泌免疫调节、络脉瘀阻与低氧微环境、痰湿阻络与酸性微环境、热毒滞络与炎症微环境、络虚不荣与免疫微环境分别具有相关性,肿瘤微环境可能是癌性疼痛络病病机的生物学基础.
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